EICOSANOIDES FUNCIONES PDF

Les prostaglandinas son, ente otros, axentes proinflamatorios y anticoagulantes. Ello forma la inestable prostaglandina G PGG de vida curtia. Los eicosanoides tienen una vida media de segundos a minutos. Cada unu ye codificado por un xen individual, y dalgunos esisten en delles formes isoformes. Ello alza los niveles de PGE 2 , faciendo a los nervios del dolor mas sensitivos.

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Acetylation of prostaglandin synthase by aspirin. Oxidative stress and cyclooxygenase-2 induction mediate cyanide-induced apoptosis of cortical cells. Toxicol Appl Pharmacol ; FitzGerald GA. COX-2 and beyond: Approaches to prostaglandin inhibition in human disease. Nat Rev Drug Discov ; 2: Prostanoid receptors: structures, properties, and functions.

Physiol Rev ; Intrahippocampal infusion of a cyclooxygenase-2 inhibitor attenuates memory acquisition in rats. Brain Res ; Distinct brain vascular cell types manifest inducible cyclooxygenase expression as a function of the strength and nature of immune insults. J Neurosci ; A novel antipyretic action of deoxy-Delta12,prostaglandin J2 in the rat brain.

Prostaglandin D2-sensitive, sleep-promoting zone defined in the ventral surface of the rostral basal forebrain. Promotion of sleep mediated by the A2a-adenosine receptor and possible involvement of this receptor in the sleep induced by prostaglandin D2 in rats.

A cyclooxygenase-2 inhibitor attenuates spontaneous and TNF-alpha-induced non-rapid eye movement sleep in rabbits. Exp Neurol ; Neurology ; Cytokine gene expression as a function of the clinical progression of Alzheimer disease dementia.

Arch Neurol ; Prostaglandins Other Lipid Mediat ; Curr Med Chem ; 8: Ann N Y Acad Sci ; Teismann P, Ferger B. Synapse ; Marked increase in cyclooxygenase-2 in ALS spinal cord: implications for therapy.

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