Enfermedades vasculares. La fisiopatogenia de la HTA es compleja y extensamente tratada en otros textos. En algunos casos se evidencian lesiones esclerosantes segmentarias y focales y puden incluso asociarse a proteinuria glomeruloesclerosis focal y segmentaria secundaria. Figura 1. Plata-metenamina, X
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Grafico de nefrona cortical y yuxtamedular. Observe la celularidad del penacho. La MBG flechas rojas. Schematic drawing of a crosssection of a glomerulus, including the afferent and efferent arterioles, the macula densa cells of the early distal tubule, the glomerular capillaries, mesangial cells, and podocytes.
En la imagen se aprecia el aparato yuxtaglomerular y algunos de los tubos renales periglomerulares. The capsule arrow of the kidney is composed of dense connective tissue with collagen fibers.
It is easily removed in the preparation of histologic specimens and, therefore, not all micrographs will exhibit the capsule. Beneath the capsule is the renal cortex with its tubules, many of which are sectioned transversely, and numerous renal corpuscles arrowheads.
Entre los corpusculos hay una zona que parece rayas. Renal Corpuscles arrows shown here, it is difficult to determine the vascular and urinary poles. The simple squamous epithelium of the outer, or parietal, layer of Bowman's capsule at the arrows encloses the glomerulus. Many of the tubules arrowheads in the vicinity of the renal corpuscle can be identified as proximal tubules. MBG Espacio urinario Capa parietal The flattened epithelial cells of Bowman's capsule rest on a basal lamina, which is continuous with the basal lamina that encloses the cells of the tubular nephron.
The urinary space of Bowman separates the parietal layer of Bowman's capsule from the cells of the visceral layer podocytes and the capillary loops of the glomerulus.
The vascular pole of the renal corpuscle A in this micrograph can be distinguished. The arrowheads Vascular pole. The endothelial cells lie just under the tips of the arrowheads, and the wall contains a single layer of smooth muscle cells. PAS, X Prolongaciones citoplasmaticas prolongaciones primarias o mayores Prolongaciones secundarias pedicelos. Pedicelos tienen un glucocalix compuesto por sialoproteinas podocalixina y podoendina de carga negativa. Three cell types make up the glomerulus: endothelial red , mesangial blue and the visceral ipithelial cellor podocyte yellow.
Squamous epithelial cells of the Bowman capsule are easily seen green. The macula densa black is part of the distal tubule. TCP The proximal tubules arrowheads are the longest and most convoluted of the tubules and, as a result, are the most numerous in sections through the renal cortex.
Extremos delgados del asa de Henle Epitelio simple plano. En las nefronas corticales tienen segmentos delgados de mm de largo. En las nefronas yuxtamedulares tienen segmentos mas largos de 9 a 10 mm llegan hasta la papila renal. Flecha verde marca la arteriola eferente y la azul la aferente. The classic simple cuboidal epithelium of collecting tubules arrows. Although it is not possible to distinguish by light microscopy between the two types of cells that form the tubules, Renal medulla The larger tubules in this image are TC.
The smaller tubules are ascending thick segments of loops of Henle. The large structure with the lumen is a papillary duct of Bellini. Its histologic features are similar to that of the collecting tubules, with the exception of the taller epithelial lining.
Papillary ducts offer a classic example of simple columnar epithelium. These ducts open at the apex of the renal pyramid, and urine flows from them into the minor calyx. Como se puede apreciar entre los tubos apenas hay tejido conjuntivo de sustento. Both the descending A and ascending B thick segments of Henle's loop are located there. In addition, the cortical portions of the collecting tubules C are also found in medullary rays Those structures that are lined by simple cuboidal epithelium and contain blood cells in their lumen are the vasa recta arrowheads The collecting tubules arrows are lined by simple cuboidal epithelium.
Collecting tubules respond to antidiuretic hormone ADH, vasopressin secreted from the neurohypophysis and control the ionic concentration of urine by becoming permeable to water, which results in the elaboration of a hypertonic urine. Henle's loop arrowheads VASOS Renal vasculature, vascular dye injection Dye injected into the vascular system highlights blood vessels in this image of renal medulla.
Vasa recta are conspicuous. Renal vasculature, vascular dye injection image of renal cortex. Glomeruli are conspicuous You just clipped your first slide! Clipping is a handy way to collect important slides you want to go back to later. Now customize the name of a clipboard to store your clips. Visibility Others can see my Clipboard. Cancel Save.